A Dual Role of P53 in Regulating Colistin-Induced Autophagy in PC-12 Cells
نویسندگان
چکیده
منابع مشابه
A Dual Role of P53 in Regulating Colistin-Induced Autophagy in PC-12 Cells
This study aimed to investigate the mechanism of p53 in regulating colistin-induced autophagy in PC-12 cells. Importantly, cells were treated with 125 μg/ml colistin for 12 and 24 h after transfection with p53 siRNA or recombinant plasmid. The hallmarks of autophagy and apoptosis were examined by real-time PCR and western blot, fluorescence/immunofluorescence microscopy, and electron microscopy...
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ژورنال
عنوان ژورنال: Frontiers in Pharmacology
سال: 2017
ISSN: 1663-9812
DOI: 10.3389/fphar.2017.00768